St. Helens & Knowsley Teaching Hospitals NHS Trust is a large acute teaching hospital trust serving the population of St. Helens and Knowsley in the North West of England. The trust provides a wide range of services, including emergency care, surgery, maternity, and mental health services. The trust also has a strong commitment to teaching and research, and is home to the University of Liverpool's Medical School.

The trust's main hospital site is Whiston Hospital, which is located in Prescot. The trust also operates two smaller hospitals, St. Helens Hospital and Knowsley Hospital. The trust employs over 7,000 staff and has an annual turnover of over £500 million.

The trust is committed to providing high-quality care to its patients. The trust has been rated as "Good" by the Care Quality Commission (CQC), the independent regulator of health and social care in England. The trust is also a member of the Academic Health Science Network (AHSN) for the North West Coast, which is a network of organizations working together to improve the health and wellbeing of the population.